High quality Dihydroartemisinin for antimalarial in stock
Dihydroartemisinin is a derivative of artemisinin, a naturally occurring compound extracted from the plant Artemisia annua (sweet wormwood). It is a potent antimalarial drug that is used to treat malaria infections caused by the Plasmodium falciparum parasite. Dihydroartemisinin is particularly effective against multidrug-resistant strains of malaria, making it a valuable treatment option in areas where other antimalarial drugs may no longer be effective. Administered either orally or intravenously, dihydroartemisinin works by targeting the parasites' vital metabolic pathways, leading to their rapid destruction and relief from malaria symptoms such as fever, chills, and headache.
Dihydroartemisinin is a highly effective antimalarial drug that exhibits potent activity against Plasmodium falciparum, the parasite that causes malaria. It works rapidly to kill the parasites, thereby relieving the symptoms of malaria, such as fever, chills, headache, and fatigue. Dihydroartemisinin is particularly useful in treating multidrug-resistant strains of malaria, where other antimalarial drugs may fail. Its rapid onset of action and high cure rates make it an important treatment option in the fight against malaria, especially in areas where the disease is prevalent and resistant to traditional drugs.
Specification
Items
Requirements
Results
Description
Appearance:
White needle crystal, odorless, taste bitter
Conforms
Solubility
Freely soluble in chloroform; soluble in acetone, sparingly soluble in methanol or ethanol; practically insoluble in water
Conforms
Melting point
145～150℃, with decomposition
146.3~146.8℃
Identification
Color Reaction
A bluish purple color is produced
Conforms
Color Reaction
A red color is produced which changes gradually to brown on standing
Conforms
Optical rotation
Should show dextral optical properties
Conforms
IR
Infrared absorption spectrum of test and standard(or infrared reference spectra No. 220) are concordant
Conforms
Test
1) Related substance
(TLC)
Single
clear spot should be obtained with solution (2). Any spot obtained with
reference solution, other than the principal spot, not more than one is
obtained, and is not more intense than the principal spot obtained with
solution (1) (2.0%).
Conforms
2) Loss on drying
≤ 0.5%
0.29%
3) Residual on Ignition
≤ 0.1%
0.07%
4) Heavy metal (TLC)
≤ 10ppm
Conforms
Assay (on dried basis)
98.0% ～102.0％ (HPLC)
99.3%
Conclusion:The product conforms to Ch.P.2010
Application
Dihydroartemisinin is primarily used in the treatment of malaria infections caused by the Plasmodium falciparum parasite. Its potent antimalarial activity, especially against multidrug-resistant strains, makes it a valuable treatment option in areas where malaria is prevalent and other drugs may be ineffective. Dihydroartemisinin can be administered either orally or intravenously, depending on the severity of the infection. It is commonly used in combination with other antimalarial drugs to achieve faster and more effective clearance of the parasites, leading to faster relief of symptoms and improved patient outcomes. Dihydroartemisinin is also being investigated for potential applications in the treatment of other parasitic diseases.
