Natural Sophora Flavescens Extract Oxymatrine Powder 98% Cas 16837-52-8

Oxymatrine, also known as Matrine N-oxide or Pachycarpidine, is a quinolizidine alkaloid extracted from the dried roots of the Sophora flavescens plant. It possesses a wide range of biological activities, including anti-inflammatory, anti-tumor, analgesic, anti-arrhythmic, antitussive, and antibacterial effects. Oxymatrine is also used in the treatment of hepatitis B virus and can inhibit iNOS expression and the TGF-β/Smad pathway. Chemically, it has the formula C15H24N2O2 and the CAS registry number 16837-52-8. It appears as a white crystalline powder that is highly soluble in water, ethanol, chloroform, and acetone, and partially soluble in ether.

product details

Function

Oxymatrine, a quinolizidine alkaloid extracted from the roots of the Sophora flavescens plant, boasts numerous benefits. Its anti-inflammatory properties help reduce swelling and alleviate pain caused by various inflammatory conditions. Additionally, Oxymatrine exhibits anti-tumor activity, making it a potential therapeutic agent in cancer treatment. Its analgesic effect can provide relief from pain, while its anti-arrhythmic properties may aid in the management of heart rhythm disorders. Oxymatrine is also known for its antitussive action, helping to suppress coughing. Furthermore, its antibacterial properties make it effective in combating bacterial infections. In the context of hepatitis B virus, Oxymatrine has been found to be beneficial in treating the virus and inhibiting iNOS expression and the TGF-β/Smad pathway, which play crucial roles in the pathogenesis of the disease. Overall, Oxymatrine's diverse biological activities offer promising therapeutic potential in various medical conditions.

Specification

Analysis	Specification	Result
Appearance	White powder	White powder
Odor	Characteristic	Characteristic
Particle size	100% pass 80 mesh	100% pass 80 mesh
Chemical Tests
Assay (HPLC) (on dry basis)	98.0% Min	98.4%
Loss on drying	5.0% Max	3.62%
Residue on Ignition	1.0% Max	0.5%
Heavy metals	10.0ppm Max	<10.0ppm
Pesticides	Negative	Negative
Microbiology Control
Total plate count	1,000cfu/g Max	<1,000cfu/g
Fungi	100cfu/g Max	<100cfu/g
Salmonella	Negative	Negative
Coli	Negative	Negative
Conclusion	Complies with the in-house standards.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

Application

Oxymatrine, an alkaloid from Sophora flavescens, finds applications in pharmaceuticals for treating inflammatory, bacterial, and viral diseases. It also serves as a pesticide in agriculture and as a catalyst in organic synthesis.